So far, no detailed recommendations are available for the treatment of individuals with LFS and cancer. It is treated according to the current treatment protocols for the respective tumor diagnosis. There are a few exceptions: For example, in LFS-associated breast cancer mastectomy is preferred to lumpectomy to reduce the risk of a second primary breast tumor and avoid radiotherapy.
For patients with medulloblastoma and LFS, a new therapy concept adapted to LFS will be offered. Please contact the HIT Study Center for more information.
If a curative therapy approach is possible, radiotherapy should be avoided. Alkylating substances and other genotoxic substances should also be avoided where acceptable. The primary treatment success remains superior to the secondary consequences.