“Germline Elongator mutations in Sonic Hedgehog medulloblastoma“

This article, published in “Nature” magazine, reports on a novel cancer predisposition gene associated with SHH medulloblastomas (SHH-MB). Furthermore, new findings on the tumor genome and the protein balance of SHH-MB are presented and discussed with regard to the mechanisms of cancer development. A click on the following button leads you directly to the article.