\"Legius Syndrome\" \u2013\u00a0What Is It?<\/h2><\/div>
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Legius syndrome is a disease caused by pathogenic variants, i.e., genetic changes in the SPRED1<\/em> gene. It is clinically similar to neurofibromatosis type 1 (NF1) due to the numerous caf\u00e9-au-lait spots on the skin (benign, light brown, uniform pigment spots). However, other manifestations of NF1 do not occur.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Overview of the Chapters on This Page:<\/h4><\/div><\/div><\/div>
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Legius Syndrome \u2013 What Is It? (This Section)<\/div><\/li><\/ul><\/div><\/div>