{"id":25265,"date":"2024-02-26T16:10:48","date_gmt":"2024-02-26T15:10:48","guid":{"rendered":"https:\/\/www.krebs-praedisposition.de\/?post_type=lexikon&p=25265"},"modified":"2025-07-14T10:59:08","modified_gmt":"2025-07-14T08:59:08","slug":"multiple-endocrine-neoplasia-type-1","status":"publish","type":"lexikon","link":"https:\/\/www.krebs-praedisposition.de\/en\/lexikon\/multiple-endocrine-neoplasia-type-1\/","title":{"rendered":"Multiple Endocrine Neoplasia Type 1"},"content":{"rendered":"
\"Multiple Endocrine Neoplasia Type 1\" \u2013\u00a0What Is It?<\/h2><\/div>
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Multiple endocrine neoplasia type 1 (MEN1, also known as Wermer syndrome) is a disease caused by pathogenic variants, i.e., genetic changes in the MEN1 gene. Those affected by MEN1 have a significantly higher risk of developing tumors of the parathyroid glands associated with hyperparathyroidism (PHPT), tumors of the islet cells of the pancreas, and anterior pituitary neuroendocrine tumors (PitNET). In total, the MEN1 tumor spectrum includes over 20 hormone-producing and non-hormone-producing tumors that can occur in various combinations.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Overview of the Chapters on This Page:<\/h4><\/div><\/div><\/div>
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Multiple Endocrine Neoplasia Type 1 \u2013 What Is It? (This Section)<\/div><\/li><\/ul><\/div><\/div>