\"Retinoblastoma Predisposition\" \u2013\u00a0What Is It?<\/h2><\/div>
<\/div><\/div><\/div><\/div>
<\/div><\/div><\/div>
Retinoblastoma is a malignant tumor of the immature retina of the eye that is caused by pathogenic variants<\/span>, i.e., genetic changes, in the RB1 <\/em>gene and usually occurs before the age of 5. The tumor can affect only one eye or both eyes. In the hereditary form of retinoblastoma, there is also an increased risk of malignant brain tumors occurring, in most cases this is pineoblastoma. Furthermore, secondary tumors such as malignant bone or soft tissue tumors (osteosarcoma or soft tissue sarcoma), tumors of the nasal cavity, the eye, and the eye socket, malignant skin tumors (melanomas), and brain tumors can occur during the disease.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Overview of the Chapters on This Page:<\/h4><\/div><\/div><\/div>
<\/i><\/span>
Retinoblastoma Predisposition \u2013 What Is It? (This Section)<\/div><\/li><\/ul><\/div><\/div>