CPS stands for “Cancer Predisposition Syndrome” and describes genetic changes that increase the risk of developing cancer.

As an individual with suspected CPS, you may think, “There’s that too!” This is often the case when the suspicion of CPS is the result of a recent cancer diagnosis or a family history of cancer. Both of these situations are stressful enough. Then comes the suspicion of CPS, which for many people means facing the possibility of other cancers throughout their lives.

With this in mind, it’s important to investigate any suspicion of CPS. If the suspicion is confirmed, intensive cancer screening may be needed to detect and treat new cancers as soon as possible. If the suspicion is not confirmed, this information is also important – and most importantly, reassuring – for those affected.

On this page we would like to provide you with information and support regarding the diagnosis of suspected CPS.

From Suspecting CPS to Clarification

Indicators of Suspected CPS

The following scenarios often raise suspicion of cancer predisposition syndrome (CPS):

  • The doctor treating you or your child has raised a concrete suspicion of CPS…

  • CPS has been identified in your family. Now you’re wondering how genetic testing is conducted for you or other relatives…
  • You have a family history of cancer and you suspect a genetic link…
  • You or your child suffer from a cancer disease, and the treating doctors have recommended genetic counseling or diagnostics…

Typically, the question of whether a patient has a CPS is answered through genetic diagnostics.

Questionnaire for Suspected CPS

The question of whether genetic diagnostics are useful cannot be answered universally and must be considered on a case-by-case basis. A questionnaire, available for download below, serves as a decision-making aid. If you or your family meet at least one criterion in this questionnaire, genetic counseling should be sought.

The questionnaire is primarily intended for healthcare professionals. We recommend that you complete it together with your treating physician or pediatrician.

Human Genetic Testing

Genetic counseling and diagnostics are typically conducted at a human genetics practice or center. If genetic counseling hasn’t already been arranged by your treating doctor, you can contact a practice or center yourself to schedule a consultation.

Find a human genetics center near you!

If you’re unable to schedule genetic counseling yourself, feel free to reach out to us. We’re here to assist you with any questions about CPS.