Welcome to our Online Portal for Cancer Predisposition Syndromes!

Prof. Christian Kratz (left) is Director of the Clinic for Pediatric Hematology and Oncology at Hannover Medical School. Prof. Dr. med. Stefan Pfister (right) is Director of the Hopp Children’s Tumor Center (KiTZ) in Heidelberg. Together they lead the largest German research consortium on cancer predisposition syndromes.

People with cancer predisposition syndromes (CPS) have a much higher risk of developing cancer due to their genetic background. Around 10% of all children and adolescents diagnosed with cancer are affected by CPS. In adults, CPS is often only diagnosed after several cancer occurrences.

Individuals with CPS face significant health challenges and require personalized treatment. Our team, consisting of scientists and pediatric oncologists, is dedicated to providing support.

We offer guidance, early detection, and treatment through our outpatient clinics. We also provide healthcare professionals with comprehensive information to assist in the care of individuals with CPS. We are also focused on research aimed at improving early detection and treatment options for CPS, as these are urgently needed.

If you have any questions about cancer predisposition syndromes or would like to support our work, please contact us! We look forward to hearing from you!

Christian Kratz & Stefan Pfister

Information for Individuals with CPS

Information for Professionals

Information on CPS Research

Help on Site – Our CPS Outpatient Services

If you or your child have been diagnosed with or are suspected of having a condition that increases the risk of cancer, we’re here to guide you through the next steps and support you in taking action. Many patients come to us for a second opinion, and we offer a range of services to help:

Information on cancer predisposition syndromes
Recommendations for early detection screenings
Assistance with scheduling early detection examinations
Treatment based on the latest medical research
Psychological support

To schedule an appointment with us in Hanover or Heidelberg and find out which documents are required, visit our outpatient clinic page by clickingthe button below.

To the outpatient services page

Find out more about our outpatient services

Information for Healthcare Professionals

If you are working with patients suspected of or diagnosed with CPS, we’re here to help. Our website offers detailed information, including:

Description of the most common types of CPS, along with diagnostic criteria, treatment considerations and early detection recommendations.
A collection of literature on CPS
The option to add your patients to our research register

We’re also happy to assist with any technical inquiries you may have. Don’t hesitate to reach out to us!

CPS Research

In medicine, there’s always more to discover, especially when it comes to cancer predisposition syndromes, where our understanding is still evolving. However, this foundational knowledge is key to developing new treatment, improving early detection, and enhancing the quality of life for those affected by CPS. That’s why we’re dedicated to our research efforts. The four buttons below will take you to the research section of our website, designed primarily for healthcare professionals. If you’re a patient and have any questions about the information, feel free to reach out to us!