Suspicion of CPS is usually followed by genetic counseling and diagnosis. If the suspicion is confirmed, the next question is what else would you like to do for your patient? A CPS-specific consultation in a special CPS outpatient clinic is often advisable. It will also discuss whether and which cancer screening tests are advisable and how they can be performed.

On this page, you will find initial tips on what to do if you suspect CPS and what may be helpful if you are diagnosed with CPS.

From Suspecting CPS to Clarification

Indicators of Suspected CPS

The following scenarios often raise suspicion of cancer predisposition syndrome (CPS):

  • Your patient has been diagnosed with a specific type of cancer.
  • There is a high incidence of cancer at a young age in the patient’s family.
  • There is consanguinity in your patient’s family.
  • Your patient has a tumor with a specific genetic alteration.
  • Your patient is young and has been diagnosed with cancer for the second or third time.
  • Your patient has congenital or syndromic anomalies.
  • Your patient is experiencing excessive toxicity during cancer treatment.

Questionnaire for suspected CPS

The question of whether genetic diagnostics are useful cannot be universally answered and must be considered on a case-by-case basis. A questionnaire, based on inquiries about family history, tumor type, somatic changes in tumor tissue, number of neoplasms, increased toxicity of therapy, and congenital anomalies, serves as a decision-making tool.

If at least one criterion is met in this questionnaire, your patient should seek genetic counseling. You can easily download the questionnaire below by clicking on the button.

From Tumor to Diagnosis

Is your patient suffering from a tumor and you suspect the presence of CPS? In that case, our CPS Navigator can assist you further. Here, you can find the underlying CPS for various tumors. If you’re searching for specific symptoms related to a CPS, simply use the search function on our “CPS Compendium” page.

CPS Diagnosis – Next Steps

Suspected CPS is usually followed by genetic counseling and diagnostics. If the suspicion is confirmed, the next question is what further steps are needed for your patient. It’s often recommended to seek CPS counseling at a specialized CPS outpatient clinic. Here, it will be discussed whether and which cancer screening tests are advisable, and how these can be conducted.

Comprehensive Information on numerous CPS can be found on our Website

In our CPS Compendium, you’ll find a wealth of information on over 50 different CPS. This section is continuously expanding to include more CPS and contains everything you need to know about the underlying genetic changes, clinical symptoms, cancer risk and spectrum, early cancer detection measures, and special treatment options.

Get in touch with our CPS Outpatient Clinics in Hanover or Heidelberg!

If your patient would like a consultation specializing in CPS, you can simply register them at one of our two outpatient clinics. You have the option of providing your patient with a one-off consultation or long-term support.

For more information and, above all, the contact details for consultation hours, please visit our outpatient clinic page.

Enrollment of your Patient in our CPS Registry and Accompanying Projects

Our research focuses on cancer predisposition syndromes. At our sites in Hanover and Heidelberg, we primarily work on improving early cancer detection and exploring new treatment options. We also evaluate the effectiveness of existing treatment concepts. By registering your patient, you’re helping us in these efforts, benefiting not only your patient but also others.