Dear patients, dear parents!
Dear colleagues!
In recent years, the detection of cell-free DNA (cfDNA) in blood has become increasingly important. This circulating cfDNA in blood contains DNA fragments from healthy cells as well as from tumor cells. The analysis of this so-called liquid biopsy should make it possible to detect the development and progress of malignant processes at an early stage and with as little invasion as possible. In addition, patterns of miRNA, methylation and proteins can be detected in the blood as a part of liquid biopsies as well. In the future, it is conceivable that this form of liquid diagnostics will also be used for therapy monitoring and aftercare. Due to the high risk of cancer in people with cancer predisposition syndromes (CPS), this blood-based and less invasive form of cancer detection is particularly promising for CPS patients.
About the Liquid Biopsy project
Criteria for participation in the Liquid Biopsy project
Requirements for registration
The Liquid Biopsy project is a subproject of the Cancer Predisposition Syndrome Registry (CPS-Registry). Therefore, registration in the CPS-Registry is a prerequisite for participation in the Liquid Biopsy project. You will find all the necessary documents on the CPS-Registry page.
Initially, liquid biopsies should only be recorded in patients with the following CPS:
Registration in the Liquid Biopsy project by the treating physician
How to proceed
Letters of information and consent as well as the delivery form for biospecimen can be found in the download area download area at the bottom of this page.
Registration in the Liquid Biopsy project by self-registration
How to registrate yourself or your child in the Liquid-Biopsy project
Blood collection and delivery
The blood collection of patients with selected CPS (see above) should be done every six months. Approximately 10 ml of blood should be taken. The blood sample can be taken as part of another diagnostic or routine blood collection.
Special blood tubes (cf-DNA Preservative Tubes of the company NORGEN) are required for the collection. We will be happy to provide these tubes. Simply contact us for this.
Downloadmaterial
In this section of our website you will find all the necessary documents to participate in the Liquid Biopsy project. Please note that different versions of the information and consent forms must be used for registration by the treating physician and for self-registration. If you have any questions regarding registration, please contact our documentation and laboratory team Beatrice Hoffmann, Birte Sänger or Christina Reimer directly.
Registration by the treating physician
Please always send blood together with the delivery form. You will find the address at the top of this page and on the delivery form.
Registration by self-registration
Please always send blood together with the delivery form. You will find the address at the top of this page and on the delivery form.
Contact persons
If you have any questions about the execution or shipment, please do not hesitate to contact us. You can contact us by telephone best in the morning.
We are gladly there for you!
Christina Reimer
Biologic Technical Assistent
| +49 511 532-7803 | |
| +49 511 532-161026 | |
| PAO.LFS-CPS@mh-hannover.de |
